Yes, yes, yes!
From my experience of working with mature students they are fantastic learners with a different outlook on life that is reflected in their work and very much valued for their contribution to the group dynamic.
Check out with each college what the entry requirements are for mature students as they are relaxed slightly in favour of life experience.
However a portfolio of work is still required and is usually assessed against the same criteria as students straight from school. For more guidance read our eBook on how to make an art portfolio for college or university.